Increased Prevalence of Alcohol Use Disorder (AUD) in Psoriasis and Dermatitis (Eczema).

Inflammatory cutaneous diseases, such as psoriasis, are associated with considerable psychosocial impact and alcohol consumption; however, this association with other skin diseases, such as dermatitis (eczema), is less explored. We examined patients with psoriasis and dermatitis for excessive alcohol consumption using the Alcohol Use Disorders Identification Test (AUDIT). For this cross-sectional, observational study, 385 patients of both genders, aged ≥18 years, who were diagnosed with either psoriasis or dermatitis, were recruited. The primary outcome measure was the AUDIT score. The prevalence of alcohol use disorder (AUD) was 28% in patients with psoriasis and 23% in patients with dermatitis. Men in both groups had statistically significant more hazardous drinking pattern (AUDIT score ≥ 8) when compared with women. The prevalence of the dermatology life quality index (DLQI) ≥ 11 was 57% in psoriasis patients and 51% in dermatitis patients. Accordingly, alcohol consumption behavior in eczema patients was comparable to those with psoriasis. Based upon the research, it is recommended that patients with inflammatory skin diseases must be asked and screened for their alcohol consumption in order to choose appropriate systemic treatment options.

Effectiveness of autoinoculation in viral warts: A single arm, open-label, and clinical trial.

Viral warts are well-defined, hyperkeratotic mucocutaneous lesions caused by human papilloma virus infection, that can occur anywhere on the body. Various medical and surgical modalities are required for treatment of warts as spontaneous regression is rarely seen. Despite the availability of multiple treatment options, warts are often recurrent and resistant to treatment. The effectiveness of autoinoculation in the treatment of multiple or recurrent verruca was evaluated. Consecutive cases with at least five warts or recurrent warts were included. A treatment-free washout period of 1 month was ensured. Patients with verruca vulgaris (n = 13), palmoplantar (n = 4), periungual (n = 5) were included in the study. The warty tissue was excised, minced and homogenous tissue implanted in a small dermal pocket in the left forearm. Patients were evaluated every 4 weeks. The procedure was repeated at 4th and 8th week. Response was assessed at each visit and at 12th week. Fifteen cases were recruited. Majority of the patients were diagnosed with verruca vulgaris (87%, n = 13) followed by periungual warts (33%, n = 5) and palmoplantar warts (27%, n = 4). Recurrent warts were present in 73% (n = 11) patients. Average improvement at the end of 12 weeks was seen in 65% cases. Ten (67%) patients showed complete resolution of warts. In two patients, warts increased in number while on treatment. Local site infection was seen in two patients. The study is limited by its small sample size. Autoinoculation is an effective modality of treatment for multiple and recurrent warts. Furthermore, it is an effective treatment modality for periungual and plantar warts, which are usually resistant to other modalities.